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You have
the ability to Transform their skin with the Obagi Nu-Derm System,
proven to correct skin functions so that skin looks and acts younger and
healthier.
The Obagi Nu-Derm System uses a unique combination of active and
prescription ingredients - including Tretinoin and Hydroquinone 4% - to
maximize penetration to all skin layers. The specific dosage and
frequency are determined and monitored by you, according to your
patient's skin condition, needs and lifestyle.
The System triggers a Therapeutic Cascade™ that:
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Increases cellular turnover of abundant, healthy keratinocytes,
pushing fresh cells to the surface more quickly and promoting
old cells to exfoliate faster |
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Suppresses melanocyte production reversing and preventing
hyperpigmentation and Rosacea |
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Promotes the even distribution of melanin, eliminating unwanted
dark patches and age spots |
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Repairs intracellular transcription of keratinocytes, producing
healthy, uniform cells for better skin structure |
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Stimulates fibroblasts to increase collagen and elastin
formation, resulting in stronger, more resilient skin |
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Increases GAG synthesis, providing natural hydration and
necessary nutrients to the epidermis |
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Increases angiogenesis, improving blood flow |
Selecting Patients
The Obagi Nu-Derm System is best for patients with
hyperpigmentation and Rosacea who are willing to commit to a
comprehensive skin care protocol and will tolerate side effects. They
also can be identified by the following:
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Concerned about mild to severe photodamage |
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Want to eliminate sun or age spots and have hyperpigmentation |
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Have fine lines, wrinkles and laxity |
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Experience adult acne or Rosacea |
Introduction: This 24-week study in 301 subjects examined the clinical
efficacy and safety of a proprietary system (Obagi Nu-Derm System)
composed of a specific protocol of cleanser, toner, alpha-hydroxy acid,
tretinoin, hydroquinone and SPF (Group 1), compared with a 0.1%
tretinoin regimen, including cleanser and SPF 30 (Group 2), 4.0%
hydroquinone regimen, including cleanser and SPF 30 (Group 3) and the
most common over-the-counter (OTC) products recommended by physicians -
cleanser, moisturizer and SPF 30 (Group 4).
Methods: Facial photodamage (perioral wrinkles, periocular wrinkles,
facial wrinkles, hyperpigmentation, Rosacea, clarity,
shallowness, tactile roughness and laxity) and irritation (erythema,
edema, scaling, papular rash, burning, stinging, itching and tightness)
were assessed by investigative clinical graders at baseline and 1, 6,
12, 18 and 24 weeks of treatment. Digital photography, ultrasound scans,
silicone replicas and full-thickness facial biopsies were also
performed.
Results: Obagi Nu-Derm System was significantly more effective
with
hyperpigmentation and Rosacea
(P²0.05)
than the other three treatments in all seven variables as demonstrated
by change from baseline in evaluations at 12 weeks and 24 weeks (Figures
1 and 2).
Conclusions: Obagi Nu-Derm System outperformed the other three regimens
(drug or OTC) at both 12 weeks and 24 weeks.
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Obagi Nu-Derm System significantly improved perioral fine
wrinkles, periocular fine wrinkles, facial fine wrinkles,
mottled hyperpigmentation, clarity, sallowness, tactile
roughness and laxity compared with the commonly prescribed
regimens of tretinoin and hydroquinone and the over-the-counter
(OTC) regimens. |
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Obagi Nu-Derm System composed of a protocol of cleanser, toner,
alpha-hydroxy acids with 0.1% tretinoin, 4.0% hydroquinone and
SPF has statistically superior efficacy in the treatment of
photodamage than other tested therapies. |
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Obagi Nu-Derm System was well tolerated when used under
appropriate supervision. |
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Other efficacy parameters will be described in a future
publication. |
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To
optimize outcomes in individuals with fine lines and wrinkles
plus laxity characteristic of photodamaged skin, clinicians
should consider treatment with drug regimens or more ideally,
with Obagi Nu-Derm System. |
I
started the Obagi [Nu-Derm] System about 2 weeks ago to correct melasma
on my face after my dermatologist recommended that I try it.
WOW! In only two weeks, most of my melasma has disappeared and the
really tough spots I've had for years are noticeably faded! I am so
delighted with your product! Even the redness and peeling (which
"I
purchased Obagi Nu-Derm System and it is wonderful. For the first time
in my entire life, I am happy with my skin. I never have been before, as
I've had acne and blotchy skin for so long. It's only been about 3
weeks, but I wanted you to know how happy I am with these products.
Thank you."
- Stephanie R., Vacaville, CA
Thanks to
such a great skin care system [Obagi Nu-Derm], my acne scars have
diminished to the level I couldn't have even imagined or hoped for with
skin care. My skin is even toned and my ice pick scars are now very
shallow. I'm no longer a targeted customer at the cosmetic counter. Some
of my friends and family are so amazed that they have [also] gone on
Obagi [Nu-Derm]."
- T. K., New York, NY |
